Metisergide [DCIT]
Brand names,
Metisergide [DCIT]
Analogs
Metisergide [DCIT]
Brand Names Mixture
Metisergide [DCIT]
Chemical_Formula
C21H27N3O2
Metisergide [DCIT]
RX_link
http://www.rxlist.com/cgi/generic3/sansert.htm
Metisergide [DCIT]
fda sheet
Metisergide [DCIT]
msds (material safety sheet)
Metisergide [DCIT]
Synthesis Reference
No information avaliable
Metisergide [DCIT]
Molecular Weight
353.458 g/mol
Metisergide [DCIT]
Melting Point
195 oC
Metisergide [DCIT]
H2O Solubility
No information avaliable
Metisergide [DCIT]
State
Solid
Metisergide [DCIT]
LogP
1.55
Metisergide [DCIT]
Dosage Forms
Tablet
Metisergide [DCIT]
Indication
For the treatment of vascular headache
Metisergide [DCIT]
Pharmacology
Methysergide has been shown, in vitro and in vivo, to inhibit or block the effects of serotonin, a substance which may be involved in the mechanism of vascular headaches. Serotonin has been variously described as a central neurohumoral agent or chemical mediator, as a "headache substance" acting directly or indirectly to lower pain threshold, as an intrinsic "motor hormone" of the gastrointestinal tract, and as a "hormone" involved in connective tissue reparative processes.
Metisergide [DCIT]
Absorption
Rapid
Metisergide [DCIT]
side effects and Toxicity
No information avaliable
Metisergide [DCIT]
Patient Information
No information avaliable
Metisergide [DCIT]
Organisms Affected
Humans and other mammals